What is one major health concern linked to individuals with Down Syndrome?

Individuals with Down syndrome often face a variety of health concerns, and one of the most significant among these is the increased prevalence of heart problems. This is primarily due to congenital heart defects, which are structural issues that are present at birth. Research indicates that about 40-60% of individuals with Down syndrome may have some form of heart defect, which can vary in severity and type, including atrioventricular septal defects, ventricular septal defects, and other conditions. These heart problems can lead to other complications, such as increased risk of respiratory infections and reduced physical endurance, highlighting the importance of early detection and intervention.

The other options, while they may be associated with various health concerns in the general population, are not as strongly linked to Down syndrome. Muscle dystrophy is more commonly related to genetic disorders that specifically affect muscle tissue, and while individuals with Down syndrome can experience muscular hypotonia (low muscle tone), this is not classified as dystrophy. Neurological disorders can occur but are not inherent to Down syndrome to the same extent as cardiac issues. Allergies occur in the general population and do not specifically correlate with Down syndrome as a major health concern. Hence, heart problems represent the most prominent and widespread health issue facing individuals with this condition